Sandeep M. Nayak, MD

The authors reply to a letter by Modesto-Lowe et al regarding their survey of psychedelic practitioners’ views on psychological support.

The survey reveals differences of opinion among psychedelic researchers, with a slight trend toward preference for an emotive approach to psychological support.

Randomized trials of psychedelics underutilize blind assessment, active drug controls, and testing psychological support against minimal-support conditions—elements that would improve quality or provide important information.

The authors note two suicidality-related events that occurred within the studies included in their recent meta-analysis.