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Alcohol Use Disorders in Primary Care
Rounds in the General Hospital

May 21, 2026

Patients with major depressive disorder and a comorbid AUD often present with more severe manifestations, including thoughts of suicide, co-occurring personality disorders, and higher rates of smoking.
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JCP
Effect of a Nationwide Aftercare Program for Self-Harm Presentations on the Risk of Self-Harm Repetition and Suicide
Original Research

May 20, 2026

Aftercare following self-harm was associated with increased risk of repeat self-harm hospital presentation and decreased risk of suicide.
, , , et al
JCP
Differential Impact of Cholecystokinin and Ghrelin on 2-Year Avoidant/Restrictive Food Intake Disorder Symptoms
Original Research

May 20, 2026

Decreases in CCK and increases in ghrelin were associated with improvements in ARFID symptomology.
, , , et al
PCC
ECT for Psychosis in Huntington Disease-Like 2
Case Report

May 19, 2026

A 47-year-old woman with genetically confirmed Huntington disease-like 2 had refractory psychosis and functional decline but responded well to electroconvulsive therapy.
, , , et al
PCC
Manifestations Associated With CNS Lesions
Rounds in the General Hospital

May 19, 2026

Neuropsychiatric manifestations of brain metastases are varied, although certain symptoms can be associated with the brain region in which there is a metastasis; lesions that affect certain parts of…
, , , et al
JCP
Rethinking Postpartum Depression: Biology, Biomarkers, and New Treatments with Jennifer L. Payne, MD
Podcast

May 19, 2026

Jennifer L. Payne, MD, discusses postpartum depression biomarkers, allopregnanolone and GABA-A receptor biology, and the clinical profile of zuranolone.
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Original Research

JCP
NNT, NNH, and LLH for Aripiprazole Once-Monthly in Schizophrenia
Original Research

May 13, 2026

Data demonstrate a favorable benefit-risk profile for aripiprazole once-monthly 400 vs placebo in acute and maintenance treatment of schizophrenia.
, , , et al
JCP
Efficacy and Safety of a Single Dose of Psilocybin for Chronic Suicidal Ideation
Original Research ▶ Video

May 13, 2026

A single psilocybin dose with psychological support was associated with rapid, large, and durable reductions in suicidal ideation and depressive symptoms.
, , , et al
JCP
Effects of Experimental Intermittent Theta Burst Stimulation on Negative Symptoms of Schizophrenia
Original Research

May 11, 2026

Findings suggest limited efficacy of experimental intermittent theta burst stimulation over the left DLPFC for negative symptoms.
, , , et al

The Journal of Clinical Psychiatry

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Systematic Review and Meta-Analysis of Use of Mood Stabilizers in Adolescents With Nonsuicidal Self-Injury
Meta-Analysis

May 18, 2026

Severity of anxiety, depression, impulsivity, and self-injury was significantly reduced following treatment with mood stabilizers.
, , , et al
JCP
Catching Cognitive Decline Early with Gary W. Small, MD
Podcast

May 5, 2026

Dr. Gary W. Small on the continuum of age-related cognitive decline: biomarkers, differential diagnosis, treatment sequencing, and lifestyle interventions for brain health.
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The Primary Care Companion for CNS Disorders

The Primary Care Companion for CNS Disorders seeks to advance the clinical expertise of primary care physicians and other health care professionals who treat patients with mental and neurologic illnesses.

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Peer Support to Prevent Suicide Among Medical Students
Letter to the Editor

May 14, 2026

The authors describe a peer support panel discussion designed to address suicide prevention, allowing medical students to actively participate in addressing critical mental health challenges they face in their…
, , , et al
PCC
Adjunct Memantine for Inappropriate Sexual Behavior
Case Report

May 14, 2026

Two patients with intellectual disability and major neurocognitive disorder exhibited inappropriate sexual behavior that significantly decreased after memantine was added as adjunctive therapy.
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