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Lumateperone as Adjunctive Therapy in Patients With Major Depressive Disorder and Anxious Distress
Original Research

Lumateperone as Adjunctive Therapy in Patients With Major Depressive Disorder and Anxious Distress

September 14, 2026

Adjunctive lumateperone 42 mg significantly improved depression and anxiety symptoms in patients with MDD with inadequate antidepressant response and anxious distress
, , , et al
JCP
Long-Acting Injectable Antipsychotics and Clozapine in Coordinated Specialty Care: Data From EPINET
Original Research

Long-Acting Injectable Antipsychotics and Clozapine in Coordinated Specialty Care: Data From EPINET

September 14, 2026

Data from the EPINET project reveal wide variation in the prescription of LAIs and clozapine across first-episode specialty care clinics.
, , , et al
PCC
Lorazepam in Chronic Catatonia Reversal
Case Report

Lorazepam in Chronic Catatonia Reversal

September 10, 2026

This report describes chronic organic catatonia following cerebral malaria in a 17-year-old male, who experienced a marked response to lorazepam.
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PCC
Vision Outcomes in Children With Mental, Emotional, Developmental, or Behavioral Problems
Original Research

Vision Outcomes in Children With Mental, Emotional, Developmental, or Behavioral Problems

September 10, 2026

This study evaluated whether vision care utilization, screening/referral steps, and vision-related outcomes differ by mental, emotional, developmental, or behavioral disorder status in US children.
, , , et al
Similar Outcomes With 2-Week and 4-Week Tapers to Xanomeline-Trospium
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Similar Outcomes With 2-Week and 4-Week Tapers to Xanomeline-Trospium

September 10, 2026

Xanomeline-trospium 2-week and 4-week taper schedules show similar discontinuation rates and tolerability in stable schizophrenia; 86% reached target dose.
Xanomeline-Trospium and EPS: Low Rates Across EMERGENT, Limited Evidence
news

Xanomeline-Trospium and EPS: Low Rates Across EMERGENT, Limited Evidence

September 10, 2026

Xanomeline-trospium EPS rates were low across EMERGENT-1, -2, and -3, but trial limitations, attrition, and no comparator data leave the motor safety profile incompletely defined.

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Original Research

JCP
Utilizing a Smartphone Application for Perinatal Depression Screening and Care Linkages
Original Research

Utilizing a Smartphone Application for Perinatal Depression Screening and Care Linkages

September 9, 2026

The prevalence of probable perinatal depression was comparable to that in US women, demonstrating the app’s ability to identify perinatal depression.
, , , et al
JCP
Using Speech to Predict MDD and GAD During Pregnancy
Original Research

Using Speech to Predict MDD and GAD During Pregnancy

September 9, 2026

Influential speech features for prediction of MDD and GAD during pregnancy were similar to those in the general population.
, , , et al
JCP
Evaluation of Sexual Function With Adjunctive Lumateperone in Major Depressive Disorder
Original Research

Evaluation of Sexual Function With Adjunctive Lumateperone in Major Depressive Disorder

September 2, 2026

Adjunctive lumateperone 42 mg did not worsen sexual functioning and was not associated with treatment-related sexual dysfunction.
, , , et al

The Journal of Clinical Psychiatry

The Journal of Clinical Psychiatry is a leader in peer-reviewed articles on mental health topics for psychiatrists and medical professionals. Now featuring The JCP Podcast: conversations with experts exploring the research shaping clinical care.  

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Voice of the Patient
Commentary

Voice of the Patient

September 9, 2026

Discusses a recent study by Bayrampour et al of the use of speech features for prediction of MDD and GAD during pregnancy.
JCP
The Regulatory Maze of Ketamine and Psychedelics with Benjamin Brody, MD
Podcast

The Regulatory Maze of Ketamine and Psychedelics with Benjamin Brody, MD

September 8, 2026

Benjamin Brody, MD, discusses ketamine’s REMS-regulated future, esketamine safety, dysphoric dissociation, and what psilocybin approval means for psychiatry.
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The Primary Care Companion for CNS Disorders

The Primary Care Companion for CNS Disorders seeks to advance the clinical expertise of primary care physicians and other health care professionals who treat patients with mental and neurologic illnesses.

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When Medical Mistakes Leave Lasting Damage
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When Medical Mistakes Leave Lasting Damage

September 8, 2026

After a medical error, tone and nonverbal cues matter; clinicians should give patients ample time to ask questions.
, , , et al
PCC
When Obsession and Psychosis Become Indistinguishable
Case Report

When Obsession and Psychosis Become Indistinguishable

September 8, 2026

Differentiating obsessions from delusions is essential for accurate diagnosis and management, as comorbid obsessive-compulsive symptoms in schizophrenia complicate treatment and may influence cognitive and affective outcomes.
, , , et al

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