Gary S. Sachs, MD

Massachusetts General Hospital, Boston, Massachusetts

  • 44Articles
  • 130.2KReads
  • 1999–2026Active
  • 136Collaborators
  • 1.4KCitations

About

Gary S. Sachs, MD, is affiliated with Massachusetts General Hospital in Boston, Massachusetts, and Signant Health in Blue Bell, Pennsylvania. Since 1999, Sachs has published extensively on bipolar disorder, major depressive disorder, suicide, addiction, mood disorders, and weight management. His work includes clinical studies and reviews on pharmacologic treatments, adjunctive therapies, and management strategies for bipolar depression and acute mania. Sachs has frequently collaborated with colleagues such as Michael E. Thase, Andrew A. Nierenberg, Charles L. Bowden, Joseph R. Calabrese, and Michael J. Ostacher.

Publications

JCP
Lumateperone as Adjunctive Therapy in Patients With Major Depressive Disorder and Anxious Distress
Original Research

Lumateperone as Adjunctive Therapy in Patients With Major Depressive Disorder and Anxious Distress

September 14, 2026

Adjunctive lumateperone 42 mg significantly improved depression and anxiety symptoms in patients with MDD with inadequate antidepressant response and anxious distress
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JCP
Adjunctive Cariprazine for MDD With Inadequate Response to Antidepressants
Original Research

Adjunctive Cariprazine for MDD With Inadequate Response to Antidepressants

August 16, 2023

This study assessed the efficacy of adjunctive use of cariprazine, an atypical antipsychotic, in MDD patients with inadequate response to antidepressants.
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PCC
Article

Factors that Impact Treatment Decisions

November 1, 2018

What patient-reported factors influence medication treatment decisions among individuals with bipolar and unipolar depression? The authors of this article conducted a survey to answer this question. Their findings may...
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JCP
Improving Outcomes in Patients With Bipolar Depression: A Comprehensive Review
InfoPack

Improving Outcomes in Patients With Bipolar Depression: A Comprehensive Review

March 25, 2015

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JCP
Commentary

Update on Best Practices for Managing Bipolar Depression

May 15, 2014

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JCP
Educational Activity

Unmet Needs in the Assessment and Management of Bipolar I Depression

June 15, 2013

JCP
Original Research

Adjunctive Oral Ziprasidone in Patients With Acute Mania Treated With Lithium or Divalproex, Part 1: Results of a Randomized, Double-Blind, Placebo-Controlled Trial

November 15, 2012

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JCP
Original Research

Adjunctive Oral Ziprasidone in Patients With Acute Mania Treated With Lithium or Divalproex, Part 2: Influence of Protocol-Specific Eligibility Criteria on Signal Detection

November 15, 2012

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JCP
NCDEU Festschrift

Pharmacologic Treatment for Bipolar

May 15, 2011

Read the full article on the pharmalogic treatment of bipolar disorders with findings supported by clinical trials.
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JCP
Original Research

Efficacy and Safety of Adjunctive Oral Ziprasidone for Acute Treatment of Depression in Patients With Bipolar I Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial

May 3, 2011

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JCP
Original Research

Antidepressant Discontinuation in Bipolar Depression: A Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) Randomized Clinical Trial of Long-Term Effectiveness and Safety

April 15, 2010

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JCP
Original Research

Clinical Features Associated With Poor Pharmacologic Adherence in Bipolar Disorder: Results From the STEP-BD Study

March 15, 2010

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Physicians Postgraduate Press, Inc. (PPP) makes no warranties about the accuracy or completeness of any information published in The Journal of Clinical Psychiatry or other PPP materials, and disclaims liability for any use or non-use of that information. Clinicians should not rely solely on these materials and should exercise their own professional judgment when making patient care decisions on an individualized basis.

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