Angela T.H. Kwan, MD(C), MSc

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About

Angela T.H. Kwan, MD(C), MSc, is affiliated with the Faculty of Medicine at the University of Ottawa and the Brain and Cognition Discovery Foundation in Canada. Kwan has published research on the relationship between ketamine and esketamine with suicidality, as well as on the use of vortioxetine for cognitive impairment in major depressive disorder during post-COVID syndrome. The work focuses on clinical topics including COVID-19, major depressive disorder, and suicide. Kwan frequently collaborates with Roger S. McIntyre and other colleagues.

Publications

JCP
Global Population-Based Study on the Association Between Ketamine and Esketamine with Suicidality Using WHO VigiBase
Original Research

Global Population-Based Study on the Association Between Ketamine and Esketamine with Suicidality Using WHO VigiBase

July 7, 2025

The results do not provide causal evidence of worsening suicidality in persons receiving esketamine/ketamine; mixed results of increased and decreased risk of suicidality were reported with both agents.
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JCP
Vortioxetine for Cognitive Impairment in MDD Post-COVID
Original Research

Vortioxetine for Cognitive Impairment in MDD Post-COVID

May 5, 2025

Measures of cognitive function and depressive symptoms improved to a greater extent with vortioxetine than with escitalopram or sertraline in post-COVID syndrome participants with MDD.
, , , et al

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