Mia C. Santucci, BA

Yale Depression Research Program, Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut

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  • 2024–2026Active
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About

Mia C. Santucci, BA, is affiliated with the Yale Depression Research Program in the Department of Psychiatry at Yale School of Medicine. Santucci has published research on the use of ketamine and esketamine in the treatment of bipolar depression and major depressive disorder, with a focus on psychotherapy interventions such as cognitive behavioral therapy for relapse prevention and the safety and efficacy of these treatments. The work spans topics including bipolar disorder, depression, psychotherapy, and suicide.

Publications

JCP
CBT following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention: The CBT-ENDURE Randomized Trial
Original Research

CBT following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention: The CBT-ENDURE Randomized Trial

May 4, 2026

In patients with major depression and suicidal ideation, adding a 16-week CBT course to esketamine led to greater improvements in suicidal ideation and depression severity than esketamine alone.
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JCP
Ketamine/Esketamine in Bipolar Depression in a Clinical Setting
Original Research

Ketamine/Esketamine in Bipolar Depression in a Clinical Setting

October 2, 2024

In a small sample of patients with bipolar depression treated with ketamine/esketamine, no evidence of mania or hypomania was seen during acute treatment.
, , , et al

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