Roopa Sethi, MD

Department of Psychiatry, Division Of Addiction Psychiatry, University of Kansas Medical Center, Kansas City, Kansas

PCC
Buprenorphine for Pain in Sickle Cell Disease
Review Article

June 16, 2026

Buprenorphine is associated with improved functional outcomes as well as reduced ED visits, hospital admissions, and opioid use in patients with chronic pain related to sickle cell disease.
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PCC
Neurological Effects of Nitrous Oxide Abuse
Case Report

July 3, 2025

A 31-year-old woman with a significant history of ketamine and N₂O addiction presented with a complicated range of neurological, neuropsychiatric, and psychiatric symptoms.
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PCC
Fentanyl-Contaminated Oxycodone
Narrative Review

November 9, 2023

The growing use of fentanyl-contaminated products is fueling the US opioid crisis. This study reviewed the rising prevalence of nonprescription fentanyl in counterfeit oxycodone, paying specific attention to oxycodone...
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PCC
Xylazine as a Fentanyl Adulterant in the US
Narrative Review

October 31, 2023

Data obtained from studies between 2006 and 2022 indicate a rapidly increasing incidence of xylazine overdose in the United States, with overdose cases now being seen in 25 states.
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PCC
Opioid Use Disorder and Its Treatment in the Elderly
Systematic Review

January 10, 2023

OUD may be particularly problematic in the elderly due to age-related pain syndromes and comorbidities that increase the risk of side effects, overdose, and death. This review assessed the...
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PCC
Rapid Microinduction of Buprenorphine in OUD
Case Report

December 27, 2022

This is the case of a patient who was transitioned from agonist therapy with methadone to sublingual buprenorphine in an outpatient setting in just 3 days.
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PCC
Case Report

November 24, 2021

There are multiple factors to consider while initiating medications for opioid use disorder. Mr A is a 66-year-old man with a 17-year history of opioid use for pain management...
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PCC
Case Report

February 18, 2021

This case report demonstrates the use of benzodiazepines to alleviate the withdrawal symptoms of phenibut in a 26-year-old man who visited the emergency department multiple times.
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PCC
Case Report

September 10, 2020

Here, read about the case of a 73-year-old man who developed hypotension, bradycardia, and possible respiratory depression following buprenorphine induction for opioid withdrawal.
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PCC
Case Report

April 23, 2020

Could prednisone therapy for Crohn's disease enhance buprenorphine metabolism, ultimately leading to a false-negative urine drug screen? Read this interesting case report to find out more.
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PCC
Case Report

February 20, 2020

Read a case report to find out more about Tapentadol and how it is often used for pain management, with low abuse potential.
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PCC
Review Article

January 30, 2020

Kratom has gained popularity as an inexpensive and accessible alternative to manage symptoms of opioid use disorder and pain. But, is it safe? This review provides the most up-to-date...
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Insightful. Evidence-based. Human-centered.

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