Rudolf Uher, MD, PhD

  • 8Articles
  • 53.2KReads
  • 2011–2023Active
  • 66Collaborators
  • 272Citations

About

Rudolf Uher, MD, PhD, is affiliated with the Department of Psychiatry at Dalhousie University in Halifax, Canada. Between 2011 and 2023, Uher has published extensively on major depressive disorder and suicide, focusing on topics such as antidepressant treatment response, prediction of suicidal ideation trajectories, and augmentation strategies. His work often involves clinical and molecular predictors of treatment outcomes and has included analyses from large-scale studies like CAN-BIND-1 and GENDEP. Frequent collaborators include Raymond W. Lam, Sidney H. Kennedy, Benicio N. Frey, Claudio N. Soares, and Daniel J. Müller.

Publications

JCP
Machine Learning Prediction of Quality of Life Improvement During Antidepressant Treatment of Patients With Major Depressive Disorder: A STAR*D and CAN-BIND-1 Report
Original Research

Machine Learning Prediction of Quality of Life Improvement During Antidepressant Treatment of Patients With Major Depressive Disorder: A STAR*D and CAN-BIND-1 Report

November 15, 2023

Quality of life is an important patient-centric outcome. Using machine learning methods, this study found that quality of life improvement with antidepressant treatment can be predicted using early depression...
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JCP
Letter to the Editor

Assessing the Interest-Activity Dimension in MDD Studies

December 8, 2020

In this letter to the editor, Dr Uher and colleagues reply to Drs Swami and Mishra.
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JCP
Original Research

Interest-Activity Levels and Need for AD Augmentation in MDD

June 16, 2020

Depressed people who have lost interest and are inactive may not respond well to antidepressants. This study examined whether depressed subjects with low interest and activity who responded poorly...
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JCP
Original Research

Trajectories of Suicidal Ideation in MDD

July 16, 2019

When are your depressed patients having suicidal thoughts during antidepressant treatment and are their ideations persistent? Identifying which 1 of the 5 distinct trajectory classes each patient is in...
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JCP
Original Research

Worsening of Suicidal Ideation During AD Treatment

May 7, 2019

Antidepressants are effective in preventing suicide, but some antidepressant-treated patients experience increased suicidal ideation. Read this article to learn if clinical features and biomarkers can predict worsened suicidal ideation...
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JCP
Original Research

CAN-BIND-1 Outcomes and Early Response Prediction in MDD

February 5, 2019

Antidepressant medications are often prescribed with little certainty about their potential effectiveness in individual patients. Can early symptom reduction help predict later symptomatic and functional outcomes of antidepressant treatment?...
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JCP
Original Research

Do Suicidal Thoughts or Behaviors Recur During a Second Antidepressant Treatment Trial?

September 18, 2012

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JCP
Article

Early and Delayed Onset of Response to Antidepressants in Individual Trajectories of Change During Treatment of Major Depression: A Secondary Analysis of Data From the Genome-Based Therapeutic Drugs for Depression (GENDEP) Study

November 15, 2011

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Physicians Postgraduate Press, Inc. (PPP) makes no warranties about the accuracy or completeness of any information published in The Journal of Clinical Psychiatry or other PPP materials, and disclaims liability for any use or non-use of that information. Clinicians should not rely solely on these materials and should exercise their own professional judgment when making patient care decisions on an individualized basis.

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