The Journal of
Clinical Psychiatry

Volume 86 • 2025 • 4

Original Research

Lumateperone as Adjunctive Therapy in Patients With Major Depressive Disorder: Results From a Randomized, Double-Blind, Phase 3 Trial

J Clin Psychiatry 2025;86(4):25m15848

Suresh Durgam, MD; Willie R. Earley, MD; Susan G. Kozauer, MD; Changzheng Chen, PhD; Hassan Lakkis, PhD; Roger S. McIntyre, MD; Stephen Stahl, MD, PhD

<em>N</em>-Acetylcysteine for the Treatment of Co-Occurring Posttraumatic Stress Disorder and Alcohol Use Disorder: A Double-Blind, Randomized Controlled Trial

Original Research

N-Acetylcysteine for the Treatment of Co-Occurring Posttraumatic Stress Disorder and Alcohol Use Disorder: A Double-Blind, Randomized Controlled Trial

J Clin Psychiatry 2025;86(4):25m15803

Sudie E. Back, PhD; Kevin Gray, MD; Amber M. Jarnecke, PhD; Tanya C. Saraiya, PhD; Elizabeth J. Santa Ana, PhD; Therese Killeen, PhD; Jane E. Joseph, PhD; James J. Prisciandaro, PhD; Delisa G. Brown, PhD; Paul J. Nietert, PhD; Tracy Stecker, PhD; Alex Rothbaum, PhD; Jennifer L. Jones, MD; Julianne C. Flanagan, PhD; Kathleen T. Brady, MD, PhD

Original Research

Five-Year Outcomes of First Suicide Attempts: Insights on Lethality, Recurrence, and Mortality

J Clin Psychiatry 2025;86(4):24m15754

Eugènia Nicolau-Subires, MD; Maria Irigoyen-Otiñano, MD, PhD; Laura Arenas-Pijoan, MD; Marina Adrados-Pérez, MD; Carla Albert-Porcar, MD; Lucía Ibarra-Pertusa, MD; María Mur-Laín, MD, PhD; Jorge Lopez-Castroman, MD, PhD; Vicent Llorca-Bofí, MD

Original Research

A Year in the Shadow of Terror: Longitudinal Effects of the October 7, 2023, Terrorist Attack on PTSD, Depression, Anxiety, and Suicidal Ideation Across Distinct Exposure Groups

J Clin Psychiatry. 2025;86(4):25m15970

Yossi Levi-Belz, PhD; Doron Amsalem, MD; Yoav Groweiss, PhD; Carmel Blank, PhD; Iris Shachar-Lavie, PhD; Yuval Neria, PhD

Original Research

Comparing the Cognitive Effects of Repeated Intravenous Ketamine and Electroconvulsive Therapy in Patients With Treatment-Resistant Depression: A Secondary Analysis of the ELEKT-D Trial

J Clin Psychiatry 2025;86(4):25m15781

Kristina T. Kumpf, MA; Samuel T. Wilkinson, MD; Bo Hu, PhD; Ruoying Chen, PhD; Kamini Krishnan, PhD; Shinjon Chakrabarti, BS; Taeho Greg Rhee, PhD; Tiffany Grezmak, MA; Sanjay J. Mathew, MD; Gerard Sanacora, MD, PhD; James W. Murrough, MD, PhD; Fernando S. Goes, MD; Katherine A. Collins, PhD; LCSW; Brian S. Barnett, MD; Amit Anand, MD

ASCP Corner

What Is Meant by the Term “Deprescribing,” and Does It Belong in Our Lexicon?

J Clin Psychiatry 2025;86(4):25ac15936

Joseph F. Goldberg, MD; Holly A. Swartz, MD; Rajnish Mago, MD; Roger S. McIntyre, MD; Gin S. Malhi, MD; Joshua D. Rosenblat, MD; Marlene P. Freeman, MD; Eduard Vieta, MD; Michael E. Thase, MD; Mauricio Tohen, MD; Leslie Citrome, MD, MPH

Letter to the Editor

Toward Consensus in Psychedelic-Assisted Therapy: The Critical Role of Psychotherapeutic Support

J Clin Psychiatry 2025;86(4):25lr15978

Vania Modesto-Lowe, MD, MPH; Deanna Sgambato, DMS, MHS; PA-C Margaret Chaplin, MD

Letter to the Editor

Psychedelic Therapies: One Drug, Multiple Treatments: Reply to Modesto-Lowe et al

J Clin Psychiatry 2025;86(4):25lr15978a

David A. Bender, MD; Sandeep M. Nayak, MD; Joshua S. Siegel, MD, PhD; David J. Hellerstein, MD; Baris C. Ercal, MD, PhD; Eric J. Lenze, MD

Volume 86 • 2025 • 4

Original Research

Lumateperone as Adjunctive Therapy in Patients With Major Depressive Disorder: Results From a Randomized, Double-Blind, Phase 3 Trial

N-Acetylcysteine for the Treatment of Co-Occurring Posttraumatic Stress Disorder and Alcohol Use Disorder: A Double-Blind, Randomized Controlled Trial

Five-Year Outcomes of First Suicide Attempts: Insights on Lethality, Recurrence, and Mortality

A Year in the Shadow of Terror: Longitudinal Effects of the October 7, 2023, Terrorist Attack on PTSD, Depression, Anxiety, and Suicidal Ideation Across Distinct Exposure Groups

Comparing the Cognitive Effects of Repeated Intravenous Ketamine and Electroconvulsive Therapy in Patients With Treatment-Resistant Depression: A Secondary Analysis of the ELEKT-D Trial

ASCP Corner

What Is Meant by the Term “Deprescribing,” and Does It Belong in Our Lexicon?

Letter to the Editor

Toward Consensus in Psychedelic-Assisted Therapy: The Critical Role of Psychotherapeutic Support

Psychedelic Therapies: One Drug, Multiple Treatments: Reply to Modesto-Lowe et al

ELSEWHERE:

FOLLOW US:

Volume 86 • 2025 • 4

Original Research

Lumateperone as Adjunctive Therapy in Patients With Major Depressive Disorder: Results From a Randomized, Double-Blind, Phase 3 Trial

N-Acetylcysteine for the Treatment of Co-Occurring Posttraumatic Stress Disorder and Alcohol Use Disorder: A Double-Blind, Randomized Controlled Trial

Five-Year Outcomes of First Suicide Attempts: Insights on Lethality, Recurrence, and Mortality

A Year in the Shadow of Terror: Longitudinal Effects of the October 7, 2023, Terrorist Attack on PTSD, Depression, Anxiety, and Suicidal Ideation Across Distinct Exposure Groups

Comparing the Cognitive Effects of Repeated Intravenous Ketamine and Electroconvulsive Therapy in Patients With Treatment-Resistant Depression: A Secondary Analysis of the ELEKT-D Trial

ASCP Corner

What Is Meant by the Term “Deprescribing,” and Does It Belong in Our Lexicon?

Letter to the Editor

Toward Consensus in Psychedelic-Assisted Therapy: The Critical Role of Psychotherapeutic Support

Psychedelic Therapies: One Drug, Multiple Treatments: Reply to Modesto-Lowe et al

Watch the New PsychCase360

Subscribe to readmore articles

Subscribe to read
more articles